The No. 3 Ohio State Buckeyes host the Iowa Hawkeyes for a Big Ten battle on Saturday afternoon. The Buckeyes are coming off a comfortable 38-7 victory over Michigan State, while the Hawkeyes knocked off Minnesota 31-14 in their last outing. Ohio State has dominated this series over the years, winning 13 of the last 15 meetings against Iowa. 

Kickoff from Ohio Stadium is at 3:30 p.m. ET on CBS and streamed live on Paramount+ (get a free 7-day trial). The Buckeyes are 20.5-point favorites in the latest Iowa vs. Ohio State odds, while the over/under for total points scored is 44.5 via SportsLine consensus.

Before making any Ohio State vs. Iowa picks or college football predictions, you NEED to see the predictions from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college spread football picks. It also went a sizzling 6-0 on all top-rated college football picks in Week 5. Anyone who has followed it has seen STRONG returns!

We can tell you it is leaning Over the total, projecting 45 combined points. It also says one side of the spread hits in 60% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Iowa vs. Ohio State, and which side of the spread hits 60% of the time? ... Join SportsLine right now to find out which side of the Ohio State vs. Iowa spread you should be all over on Saturday, all from the model that is up well over $2,000 since its inception!